Nico OโReilly, who played for Manchester City at left-back last season, is also in the squad but came through his ranks at the Etihad Stadium as a midfielder. Dan Byrne also played at left back but is considered a centre-back.
Spence and centre-backs Jarel Quansah and Konsa are Tuchelโs alternative options at right-back.
However, Tuchel said: โYes, I am happy (with my options at right-back). I have chosen the team, so I am very happy with all the characteristics of the players and the strengths they give us.
โWe would like every key player to be available, but thatโs not the case โ we find solutions, thatโs what we do. This is a tournament, we move on.โ
Tuchel, however, is confident James will play again at the World Cup.
โItโs a small hamstring problem, he hasnโt been able to train for the last two days,โ the German confirmed.
โHeโs currently on an accelerated rehabilitation program and weโre taking it game by game, but weโre very confident heโll be available (during the tournament).โ
There was more good news regarding the availability of Bukayo Saka, Declan Rice and Elliot Anderson, who Tuchel said would be available to face Panama.
Rice (calves) and Anderson (glutes) missed Thursdayโs practice but returned Friday.
Tuchel confirmed Saka is ready to start after leaving the bench for the first two matches with a long-term complaint of Achilles tendinitis.