“We have to be careful with that because then the national tournaments will lose their essence,” said McIlroy, a two-time Masters champion.
“You can’t call yourself a national open tournament anymore if it’s a closed tournament and there’s a certain number of guys in it.
“These events need to be treated differently than the Travelers Championship or the RBC Heritage or whatever the championship series is going to be.”
The Scottish Open is co-hosted by the PGA and DP World Tours from 2022.
This means that it can be played by members of any tour as long as they are ranked high enough to qualify for the 156-man tournament.
Approved by PGA Tour CEO Brian Rolapp, the plan will see around 120 players compete at championship level vying for a prize fund of at least $20 million (£15 million).
The prize fund for the Scottish Open is £6.7 million, but McIntyre said: “Personally, I think the Scottish Open will be absolutely fine.
“I don’t think this is a $20 million event. I see this is a Rolex Series/European Tour event. It would be a little crazy to host a $20 million event in Scotland, given the world we live in today. It’s not the same as in America.”
Many top Americans are excited to take part in the Scottish Open to sharpen their game on the seaside courses ahead of The Open next week.
“It has to work within the new schedule,” said world number one and reigning Open champion Scotty Scheffler.
“It’s important that we keep it in the Championship Series just because there are so many guys coming here and playing the week before (The Open).”
Scheffler said it was “hard to say” whether the new lineup should also include DP World Tour players.
“In golf it’s very difficult to rank players when they don’t play together all the time,” said the 30-year-old American.
“Having similar guys playing against each other on great golf courses week after week is the best way to structure our schedule.
“It would be great if this tournament fit into that mold.”